2021 Research

Here is a sample of Pitt research papers published in 2021 in journals with impact factors of 5 or higher. Click on the journal title to read a specific PubMed citation.

Neurotherapeutics. 2021 Dec 21
Genomics and Functional Genomics of Alzheimer's Disease
M Ilyas Kamboh 

Brain Behav Immun. 2021 Dec 4
ICAM-1 protects neurons against Amyloid-β and improves cognitive behaviors in 5xFAD mice by inhibiting NF-κB
Subhalakshmi Guha, Paidi Ramesh Kumar, Soumita Goswami, Pampa Saha, Subhas C Biswas

Addiction. 2021 Dec 3
Momentary associations between stress and alcohol craving in the naturalistic environment: differential associations for Black and White young adults
Sarah L Pedersen, Traci M Kennedy, Jordan Holmes, Brooke S G Molina

Alzheimers Dement. 2021 December
Genome-wide meta-analysis of age-related cognitive decline in population-based older individuals
Vibha Acharya, Kang-Hsien Fan, Beth E Snitz, Mary Ganguli, Steve DeKosky, Oscar L Lopez, Eleanor Feingold, M Ilyas Kamboh 

Int J Mol Sci. 2021 Nov 23
Contributes to Mid-Hindbrain Patterning by Regulation of mdDA Neuronal Cell-Fate and Repression of a Hindbrain-Specific Cell-Fate
Willemieke M Kouwenhoven, Lars von Oerthel, Maria Gruppilo, Jianmin Tian, Cindy M R J Wagemans, Imke G J Houwers, Joseph Locker, Simone Mesman, Marten P Smidt 

J Neurosci. 2021 Nov 10
Silent Synapses in Cocaine-Associated Memory and Beyond
William J Wright, Yan Dong

J Invest Dermatol  2021 Nov 6
Neuron‒Mast Cell Cross-Talk in the Skin
Shiqun Zhang, Tina L Sumpter, Daniel H Kaplan

Brain Stimul. 2021 Nov 5
Deep brain stimulation effect on anterior pallidum reduces motor impulsivity in Parkinson's disease
Khaled Moussawi, Min Jae Kim, Sydney Baybayan, Myles Wood, Kelly A Mills

PLoS Genet. 2021 Nov 4
Serotonin transporter-mediated molecular axis regulates regional retinal ganglion cell vulnerability and axon regeneration after nerve injury
Rody Kingston, Dwarkesh Amin, Sneha Misra, Jeffrey M Gross, Takaaki Kuwajima

Pain. 2021 Nov 1
Peripheral GABAA receptor signaling contributes to visceral hypersensitivity in a mouse model of colitis
Emanuel Loeza-Alcocer, Michael S Gold

Biol Psychiatry. 2021 Nov 1
Polygenic Scores for Psychiatric Disorders: One Important Piece of the Risk Prediction Puzzle
Maria Jalbrzikowski

J Consult Clin Psychol  2021 November
Extracurricular involvement in the school-age period and adolescent problem behavior among low-income youth
Julia S Feldman, Yiyao Zhou, Chelsea Weaver Krug , Melvin N Wilson, Kathryn Lemery-Chalfant, Daniel S Shaw

Nat Cancer. 2021 November
Future directions in preclinical and translational cancer neuroscience research
Ihsan Ekin Demir, Carmen Mota Reyes, Wasfi Alrawashdeh, Güralp O Ceyhan, Sylvie Deborde, Helmut Friess, Kıvanç Görgülü, Rouzanna Istvanffy, David Jungwirth, Rohini Kuner, Maria Maryanovich, Shorook Na'ara, Simon Renders, Jami L Saloman, Nicole N Scheff, Hendrik Steenfadt, Pavel Stupakov, Vera Thiel, Divij Verma, Bengi Su Yilmaz, Ruth A White, Timothy C Wang, Richard J Wong, Paul S Frenette, Ziv Gil, Neural Influences in Cancer (NIC) International Research Consortium; Brian M Davis

Curr Biol 2021 Oct 28
Transcriptional and anatomical diversity of medium spiny neurons in the primate striatum
Jing He, Michael Kleyman, Jianjiao Chen, Aydin Alikaya, Kathryn M Rothenhoefer, Bilge Esin Ozturk, Morgan Wirthlin, Andreea C Bostan, Kenneth Fish, Leah C Byrne, Andreas R Pfenning, William R Stauffer

Curr Opin Biotechnol. 2021 Oct 25
Bio-integrative design of the neural tissue-device interface
Delin Shi, Vaishnavi Dhawan, Xinyan Tracy Cui

Int J Mol Sci. 2021 Oct 21
Post-Stroke Timing of ECM Hydrogel Implantation Affects Biodegradation and Tissue Restoration
Corina Damian, Harmanvir Ghuman, Carrinton Mauney, Reem Azar, Janina Reinartz, Stephen F Badylak, Michel Modo

Neurosci Biobehav Rev. 2021 Oct 5
Promoting brain health through physical activity among adults exposed to early life adversity: Potential mechanisms and theoretical framework
Shannon D Donofry, Chelsea M Stillman, Jamie L Hanson, Margaret Sheridan, Shufang Sun, Eric B Loucks, Kirk I Erickson

Sci Rep . 2021 Oct 4
Sensory integration abilities for balance in glaucoma, a preliminary study
Caitlin O'Connell, Mark Redfern, Kevin C Chan, Gadi Wollstein, Ian P Conner, Rakié Cham

Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Oct 1
Imaging the influence of red blood cell docosahexaenoic acid status on the expression of the 18KDa translocator protein in the brain: a [ 11 C]PBR28 PET study in young healthy males
Savannah Tollefson, Michael L Himes, Katelyn M Kozinski, Brian J Loprest, N Scott Mason, Joseph Hibbeln, Matthew F Muldoon, Rajesh Narendran

Neuroimage. 2021 Sep 17
Neural dynamics underlying the acquisition of distinct auditory category structures
Gangyi Feng, Zhenzhong Gan, Han Gyol Yi, Shawn W Ell, Casey L Roark, Suiping Wang, Patrick C M Wong, Bharath Chandrasekaran

Cereb Cortex. 2021 Sep 1
Articulatory Gain Predicts Motor Cortex and Subthalamic Nucleus Activity During Speech
C Dastolfo-Hromack, A Bush, A Chrabaszcz, A Alhourani, W Lipski, D Wang, D J Crammond, S Shaiman, M W Dickey, L L Holt, R S Turner, J A Fiez, R M Richardson

Transl Psychiatry. 2021 Sep 1
Biobehavioral correlates of an fMRI index of striatal tissue iron in depressed patients
Rebecca B Price, Brenden C Tervo-Clemmens, Benjamin Panny, Michelle Degutis, Angela Griffo, Mary Woody

Neuroinflammation. 2021 Aug 28
Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function
Qian Liu, Mohammad Iqbal H Bhuiyan, Ruijia Liu, Shanshan Song, Gulnaz Begum, Cullen B Young, Lesley M Foley, Fenghua Chen, T Kevin Hitchens, Guodong Cao, Ansuman Chattopadhyay, Li He, Dandan Sun

Nat Med. 2021 Aug 26
Microglial activation and tau propagate jointly across Braak stages
Tharick A Pascoal, Andrea L Benedet, Nicholas J Ashton, Min Su Kang, Joseph Therriault, Mira Chamoun, Melissa Savard, Firoza Z Lussier, Cécile Tissot, Thomas K Karikari, Julie Ottoy, Sulantha Mathotaarachchi, Jenna Stevenson, Gassan Massarweh, Michael Schöll, Mony J de Leon, Jean-Paul Soucy, Paul Edison, Kaj Blennow, Henrik Zetterberg, Serge Gauthier, Pedro Rosa-Neto

J Neurosci. 2021 Aug 26
Mechanisms underlying the selective therapeutic efficacy of carbamazepine for attenuation of trigeminal nerve injury pain
Jorge Baruch Pineda-Farias, Emanuel Loeza-Alcocer, Vidhya Nagarajan, Michael S Gold, Raymond Sekula

Mol Neurobiol. 2021 Aug 25
Reductions in Synaptic Vesicle Glycoprotein 2 Isoforms in the Cortex and Hippocampus in a Rat Model of Traumatic Brain Injury
Katherine M Fronczak, Youming Li, Jeremy Henchir, C Edward Dixon, Shaun W Carlson

Sleep. 2021 Aug 25
A trait of mind: stability and robustness of sleep across sleep opportunity manipulations during simulated military operational stress
Alice D LaGoy, J David Cashmere, Meaghan E Beckner, Shawn R Eagle, Aaron M Sinnott, William R Conkright, Eric Miller, Carson Derrow, Michael N Dretsch, Shawn D Flanagan, Bradley C Nindl, Christopher Connaboy, Anne Germain, Fabio Ferrarelli

Annu Rev Med. 2021 Aug 20
Neurologic Manifestations and Complications of COVID-19
Matthew K Hensley, Desiree Markantone, Hallie C Prescott

Neurobiol Dis. 2021 Aug 17
Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer's disease
Nicholas F Fitz, Jiebiao Wang, M Ilyas Kamboh, Radosveta Koldamova, Iliya Lefterov

J Biol Chem. 2021 Aug 16
The complement cascade in the regulation of neuroinflammation, nociceptive sensitization, and pain
Charles A Warwick, Alex L Keyes, Trent M Woodruff, Yuriy M Usachev

Neuropsychopharmacology. 2021 Aug 16
The prefrontal cortex and OCD
Susanne E Ahmari, Scott L Rauch 

Biomaterials. 2021 Aug 12
Long-term in vivo two-photon imaging of the neuroinflammatory response to intracortical implants and micro-vessel disruptions in awake mice
Qianru Yang, Alberto L Vazquez, Xinyan Tracy Cui 

Nat Commun. 2021 Aug 11
Cell-type and subcellular compartment-specific APEX2 proximity labeling reveals activity-dependent nuclear proteome dynamics in the striatum
V Dumrongprechachan, R B Salisbury, G Soto, M Kumar, M L MacDonald, Y Kozorovitskiy

Immunol Cell Biol. 2021 Aug 5
Neuroimmunology of cancer and associated symptomology
Nicole N Scheff, Jami L Saloman

Nat Neurosci. 2021 Aug 5.
Neural fragility as an EEG marker of the seizure onset zone
Adam Li, Chester Huynh, Zachary Fitzgerald, Iahn Cajigas, Damian Brusko, Jonathan Jagid, Angel O Claudio, Andres M Kanner, Jennifer Hopp, Stephanie Chen, Jennifer Haagensen, Emily Johnson, William Anderson, Nathan Crone, Sara Inati, Kareem A Zaghloul, Juan Bulacio, Jorge Gonzalez-Martinez#, Sridevi V Sarma#

J Parkinsons Dis. 2021 Aug 4
An Update on Gene Therapy Approaches for Parkinson's Disease: Restoration of Dopaminergic Function
Amber D Van Laar, Victor S Van Laar, Waldy San Sebastian, Aristide Merola, J Bradley Elder, Russell R Lonser, Krystof S Bankiewicz

J Neuroinflammation  2021 Jul 31
Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain
Xinfeng Guo, Clayton A Wiley, Richard A Steinman, Yi Sheng, Beihong Ji, Junmei Wang, Liyong Zhang, Tony Wang, Mazen Zenatai, Timothy R Billiar, Qingde Wang

Prog Neurobiol. 2021 Jul 29
Adiponectin ameliorates hypoperfusive cognitive deficits by boosting a neuroprotective microglial response
Wanying Miao, Liyuan Jiang, Fei Xu, Junxuan Lyu, Xiaoyan Jiang, Maxine He, Yaan Liu, Tuo Yang, Rehana K Leak, R Anne Stetler, Jun Chen, Xiaoming Hu

Elife 2021 Jul 27
Perception of microstimulation frequency in human somatosensory cortex
Christopher L Hughes, Sharlene N Flesher, Jeffrey M Weiss, Michael L Boninger, Jennifer Collinger, Robert Gaunt

Neuron. 2021 Jul 22
RNA modulates physiological and neuropathological protein phase transitions
Jacob R Mann, Christopher J Donnelly 

Neurobiol Dis. 2021 Jul 20
Two hit mitochondrial-driven model of synapse loss in neurodegeneration
S V Baranov, A Jauhari, D L Carlisle, R M Friedlander

Neuropsychopharmacology. 2021 Jul 20
Differentiating white matter measures that protect against vs. predispose to bipolar disorder and other psychopathology in at-risk youthRenata Rozovsky, Amelia Versace, Lisa K Bonar, Michele Bertocci, Cecile D Ladouceur, Jay Fournier, Kelly Monk, Halimah Abdul-Waalee, Genna Bebko, Danella Hafeman, Dara Sakolsky, Tina Goldstein, Boris Birmaher, Mary L Phillips 

Neuropharmacology. 2021 Jul 17
Sustained treatment with an α5 GABA A receptor negative allosteric modulator delays excitatory circuit development while maintaining GABAergic neurotransmissionJessica L Nuwer, Megan L Brady, Nadya V Povysheva, Amanda Coyne, Tija C Jacob

J Cereb Blood Flow Metab. 2021 Jul 14
Intranasal delivery of interleukin-4 attenuates chronic cognitive deficits via beneficial microglial responses in experimental traumatic brain injury
Hongjian Pu, Cheng Ma, Yongfang Zhao, Yangfan Wang, Wenting Zhang, Wanying Miao, Fang Yu, Xiaoming, Yejie Shi, Rehana K Leak, T Kevin Hitchens, C Edward Dixon, Michael Vl Bennett, Jun Chen 

Curr Biol. 2021 Jul 12
Decision making: Making sense of non-sensory neurons
Chris C Rodgers, Badr F Albanna, Michele N Insanally

Neuropsychopharmacology. 2021 Jul 7
PFC neuromodulation with theta burst stimulation to impact behavior and neural network activity in schizophrenia and bipolar disorder
Fabio Ferrarelli, Mary L Phillips 

PLoS Pathog. 2021 Jul 6
Varicella-zoster virus early infection but not complete replication is required for the induction of chronic hypersensitivity in rat models of postherpetic neuralgia
Benjamin E Warner, Michael B Yee, Mingdi Zhang, Rebecca S Hornung, Benedikt B Kaufer, Robert J Visalli, Phillip R Kramer, William F Goins, Paul R Kinchington 

Neurobiol Stress. 2021 Jul 2
Glucagon-like peptide 1 receptor-mediated stimulation of a GABAergic projection from the bed nucleus of the stria terminalis to the hypothalamic paraventricular nucleus
Nadya Povysheva, Huiyuan Zheng, Linda Rinaman

JAMA Netw Open. 2021 Jul 1
Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury
Ruchira M Jha, Benjamin E Zusman , Ava M Puccio, David O Okonkwo, Matthew Pease, Shashvat M Desai, Matthew Leach, Yvette P Conley, Patrick M Kochanek

Pain. 2021 Jul 1
MrgprdCre lineage neurons mediate optogenetic allodynia through an emergent polysynaptic circuit
Charles Warwick, Colleen Cassidy, Junichi Hachisuka, Margaret C Wright, Kyle M Baumbauer, Peter C Adelman, Kuan H Lee, Kelly M Smith, Tayler D Sheahan, Sarah E Ross, H Richard Koerber

Mol Psychiatry. 2021 Jun 30
Thalamic reticular nucleus impairments and abnormal prefrontal control of dopamine system in a developmental model of schizophrenia: prevention by N-acetylcysteine
Xiyu Zhu #, Jan-Harry Cabungcal #, Michel Cuenod, Daniela L Uliana, Kim Q Do, Anthony A Grace

Neuropathol Appl Neurobiol  2021 Jun 23
G protein-coupled receptor kinases are associated with Alzheimer's disease pathology
Thais Rafael Guimarães, Eric Swanson, Julia Kofler, Amantha Thathiah 

Biosens Bioelectron. 2021 Jun 16
3D fuzzy graphene microelectrode array for dopamine sensing at sub-cellular spatial resolution
Elisa Castagnola, Raghav Garg, Sahil K Rastogi, Tzahi Cohen-Karni, Xinyan Tracy Cui

PLoS Biol. 2021 Jun 16
Neuronal selectivity to complex vocalization features emerges in the superficial layers of primary auditory cortex
Pilar Montes-Lourido, Manaswini Kar, Stephen V David, Srivatsu Sadagopan 

Biol Psychiatry. 2021 Jun 12
Transcriptional Alterations in Dorsolateral Prefrontal Cortex and Nucleus Accumbens Implicate Neuroinflammation and Synaptic Remodeling in Opioid Use Disorder
Marianne L Seney, Sam-Moon Kim, Jill R Glausier, Mariah A Hildebrand, Xiangning Xue, Wei Zong, Jiebiao Wang, Micah A Shelton, BaDoi N Phan, Chaitanya Srinivasan, Andreas R Pfenning, George C Tseng, David A Lewis, Zachary Freyberg, Ryan W Logan

Mol Aspects Med. 2021 Jun 12
Neuronal autophagy and mitophagy in Parkinson's disease
Britney N Lizama, Charleen T Chu 

Mol Psychiatry. 2021 Jun 10
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease
Mary Ann A DeMichele-Sweet, Lambertus Klei, Byron Creese, Janet C Harwood, Elise A Weamer, Lora McClain, Rebecca Sims, Isabel Hernandez, Sonia Moreno-Grau, Lluís Tárraga, Mercè Boada, Emilio Alarcón-Martín, Sergi Valero, NIA-LOAD Family Based Study Consortium, Alzheimer’s Disease Genetics Consortium (ADGC); Yushi Liu, Basavaraj Hooli Dag Aarsland, Geir Selbaek, Sverre Bergh, Arvid Rongve, Ingvild Saltvedt, Håvard K Skjellegrind, Bo Engdahl, Eystein Stordal, Ole A Andreassen, Srdjan Djurovic, Lavinia Athanasiu, Davide Seripa, Barbara Borroni, Diego Albani, Gianluigi Forloni, Patrizia Mecocci, Alessandro Serretti, Diana De Ronchi, Antonis Politis, Julie Williams, Richard Mayeux, Tatiana Foroud, Agustin Ruiz, Clive Ballard, Peter Holmans, Oscar L Lopez, M Ilyas Kamboh, Bernie Devlin, Robert A Sweet 

Neurosci Biobehav Rev. 2021 Jun 8
Glucocorticoid Resistance and β2-Adrenergic Receptor Signaling Pathways Promote Peripheral Pro-Inflammatory Conditions Associated with Chronic Psychological Stress: A Systematic Review Across Species
Catherine P Walsh, Dana H Bovbjerg, Anna L Marsland 

Nat Commun. 2021 Jun 7
Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease
Nicholas F Fitz #, Kyong Nyon Nam #, Cody M Wolfe # Florent Letronne, Brittany E Playso, Bistra E Iordanova, Takashi D Y Kozai, Richard J Biedrzycki, Valerian E Kagan, Yulia Y Tyurina, Xianlin Han, Iliya Lefterov, Radosveta Koldamova 

J Neurosci. 2021 Jun 7
Multiple adjoining word- and face-selective regions in ventral temporal cortex exhibit distinct dynamics
Matthew J Boring, Edward H Silson, Michael J Ward, R Mark Richardson, Julie A Fiez, Chris I Baker, Avniel Singh Ghuman 

Curr Dir Psychol Sci. 2021 Jun 1
Developmental Variability and Developmental Cascades: Lessons from Motor and Language Development in Infancy
Jana M Iverson

Acta Neuropathol. 2021 Jun 1
DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner
Tyler R Fortuna, Sukhleen Kour, Eric N Anderson, Caroline Ward, Dhivyaa Rajasundaram, Christopher J Donnelly, Andreas Hermann, Hala Wyne, Frank Shewmaker, Udai Bhan Pandey

Neuropsychopharmacology. 2021 May 31
Dissociating default mode network resting state markers of suicide from familial risk factors for depression
Henry W Chase, Randy P Auerbach, David A Brent, Jonathan Posner, Myrna M Weissman, Ardesheer Talati 

J Gerontol A Biol Sci Med Sci. 2021 May 28
Mild parkinsonian signs, energy decline, and striatal volume in community-dwelling older adults
Qu Tian, Rebecca Ehrenkranz, Andrea L Rosso, Nancy W Glynn, Lana M Chahine, James Hengenius, Xiaonan Zhu, Caterina Rosano 

Biol Psychiatry. 2021 Mar 26
Patterns of Infant Amygdala Connectivity Mediate the Impact of High Caregiver Affect on Reducing Infant Smiling: Discovery and Replication
Mary L Phillips, Vincent J Schmithorst, Layla Banihashemi, Megan Taylor, Alyssa Samolyk, Jessie B Northrup, Gabrielle E English, Amelia Versace, Richelle S Stiffler, Haris A Aslam, Lisa Bonar, Ashok Panigrahy, Alison E Hipwell 

Mol Psychiatry. 2021 May 25
White matter abnormalities associated with ADHD outcomes in adulthood
A Versace, N P Jones, H M Joseph, R A Lindstrom, T K Wilson, J P Lima Santos, E M Gnagy, W E Pelham Jr, C D Ladouceur #, B S G Molina #

Proc Natl Acad Sci U S A   2021 May 25
The immune response is a critical regulator of zebrafish retinal pigment epithelium regeneration
Lyndsay L Leach. Nicholas J Hanovice, Stephanie M George, Ana E Gabriel, Jeffrey M Gross

Nat Med. 2021 May 24
Partial recovery of visual function in a blind patient after optogenetic therapy
José-Alain Sahel, Elise Boulanger-Scemama, Chloé Pagot, Angelo Arleo, Francesco Galluppi, Joseph N Martel, Simona Degli Esposti, Alexandre Delaux, Jean-Baptiste de Saint Aubert, Caroline de Montleau, Emmanuel Gutman, Isabelle Audo, Jens Duebel, Serge Picaud, Deniz Dalkara, Laure Blouin, Magali Taiel, Botond Roska 

Sci Rep. 2021 May 24
Assessment of optogenetically-driven strategies for prosthetic restoration of cortical vision in large-scale neural simulation of V1
Jan Antolik, Quentin Sabatier, Charlie Galle, Yves Frégnac, Ryad Benosman

Adv Healthc Mater. 2021 May 24
Electrode Materials for Chronic Electrical Microstimulation
Xin Sally Zheng, Chao Tan, Elisa Castagnola, Xinyan Tracy Cui 

Science. 2021 May 21
A brain-computer interface that evokes tactile sensations improves robotic arm control
Sharlene N Flesher, John E Downey, Jeffrey M Weiss, Christopher L Hughes, Angelica J Herrera, Elizabeth C Tyler-Kabara, Michael L Boninger. Jennifer L Collinger #, Robert A Gaunt # 

Cereb Cortex. 2021 May 17
Direct Interhemispheric Cortical Communication via Thalamic Commissures: A New White-Matter Pathway in the Rodent Brain
Diego Szczupak, Pamela Meneses Iack, Cirong Liu, IRC5 Consortium; Fernanda Tovar-Moll, Roberto Lent, Afonso C Silva

Am J Sports Med. 2021 May 12
Discriminative Validity of Vestibular Ocular Motor Screening in Identifying Concussion Among Collegiate Athletes: A National Collegiate Athletic Association-Department of Defense Concussion Assessment, Research, and Education Consortium Study
Anthony P Kontos, Shawn R Eagle, Gregory Marchetti, Aaron Sinnott, Anne Mucha, Nicholas Port, Lyndsey M Ferris, R J Elbin, Jay Clugston, Justus Ortega, Steven P Broglio, Thomas McAllister, Michael McCrea, Paul Pasquina, CARE Consortium Site Investigators; Alison Brooks, Thomas Buckley, Jason Mihalik, Christopher Miles, Michael W Collins

Curr Biol. 2021 May 10
Olfaction: How mixing masks privilege
Tenzin Kunkhyen, Claire E J Cheetham

Alzheimers Res Ther. 2021 May 10
Validation of amyloid PET positivity thresholds in centiloids: a multisite PET study approach
Sarah K Royse, Davneet S Minhas, Brian J Lopresti, Alice Murphy, Tyler Ward, Robert A Koeppe, Santiago Bullich, Susan DeSanti, William J Jagust, Susan M Landau, Alzheimer’s Disease Neuroimaging Initiative

Mol Psychiatry. 2021 May 7
Cocaine-induced projection-specific and cell type-specific adaptations in the nucleus accumbens
Alexander K Zinsmaier, Yan Dong, Yanhua H Huang 

Nat Commun. 2021 May 7
Loss of function mutations in GEMIN5 cause a neurodevelopmental disorder
Sukhleen Kour #, Deepa S Rajan #, Tyler R Fortuna, Eric N Anderson, Caroline Ward, Youngha Lee, Sangmoon Lee, Yong Beom Shin, Jong-Hee Chae, Murim Choi, Karine Siquier, Vincent Cantagrel, Jeanne Amiel, Elliot S Stolerman, Sarah S Barnett, Margot A Cousin, Diana Castro, Kimberly McDonald, Brian Kirmse, Andrea H Nemeth, Dhivyaa Rajasundaram, A Micheil Innes, Danielle Lynch, Patrick Frosk, Abigail Collins, Melissa Gibbons, Michele Yang, Isabelle Desguerre, Nathalie Boddaert, Cyril Gitiaux, Siri Lynne Rydning, Kaja K Selmer, Roser Urreizti, Alberto Garcia-Oguiza, Andrés Nascimento Osorio, Edgard Verdura, Aurora Pujol, Hannah R McCurry, John E Landers, Sameer Agnihotri, E Corina Andriescu, Shade B Moody, Chanika Phornphutkul, Maria J Guillen Sacoto, Amber Begtrup, Henry Houlden, Janbernd Kirschner, David Schorling, Sabine Rudnik-Schöneborn, Tim M Strom, Steffen Leiz, Kali Juliette, Randal Richardson, Ying Yang, Yuehua Zhang, Minghui Wang, Jia Wang, Xiaodong Wang, Konrad Platzer, Sandra Donkervoort, Carsten G Bönnemann, Matias Wagner, Mahmoud Y Issa, Hasnaa M Elbendary, Valentina Stanley, Reza Maroofian, Joseph G Gleeson, Maha S Zaki, Jan Senderek, Udai Bhan Pandey

AMA Netw Open. 2021 May 3
Global Incidence of Neurological Manifestations Among Patients Hospitalized With COVID-19-A Report for the GCS-NeuroCOVID Consortium and the ENERGY Consortium
Sherry H-Y Chou Ettore Beghi, Raimund Helbok, Elena Moro, Joshua Sampson, Valeria Altamirano, Shraddha Mainali, Claudio Bassetti, Jose I Suarez, Molly McNett, GCS-NeuroCOVID Consortium and ENERGY Consortium

Transl Psychiatry. 2021 May 1
Imaging beta-amyloid (Aβ) burden in the brains of middle-aged individuals with alcohol-use disorders: a [ 11 C]PIB PET study
Margaret R Flanigan #, Sarah K Royse #, David P Cenkner, Katelyn M Kozinski, Clara J Stoughton, Michael L Himes, Davneet S Minhas, Brian Lopresti, Meryl A Butters, Rajesh Narendran 

Neurobiol Dis. 2021 Apr 30
Kcns3 deficiency disrupts Parvalbumin neuron physiology in mouse prefrontal cortex: Implications for the pathophysiology of schizophrenia
Takeaki Miyamae, Takanori Hashimoto, Monica Abraham, Rika Kawabata, Sho Koshikizawa, Yufan Bian, Yosuke Nishihata, Mitsuru Kikuchi, G Bard Ermentrout, David A Lewis, Guillermo Gonzalez-Burgos 

Schizophr Bull. 2021 Apr 30
Peripubertal mGluR2/3 Agonist Treatment Prevents Hippocampal Dysfunction and Dopamine System Hyperactivity in Adulthood in MAM Model of Schizophrenia
Susan F Sonnenschein, Anthony A Grace 

J Cereb Blood Flow Metab. 2021 Apr 28
Genetic deletion of endothelial microRNA-15a/16-1 promotes cerebral angiogenesis and neurological recovery in ischemic stroke through Src signaling pathway
Ping Sun, Feifei Ma, Yang Xu, Chao Zhou, R Anne Stetler, Ke-Jie Yin 

Aging Cell. 2021 Apr 28
Vesicular glutamate transporter modulates sex differences in dopamine neuron vulnerability to age-related neurodegeneration
Silas A Buck, Thomas Steinkellner, Despoina Aslanoglou, Michael Villeneuve, Sai H Bhatte, Victoria C Childers, Sophie A Rubin, Briana R De Miranda, Emma I O'Leary, Elizabeth G Neureiter, Keri J Fogle, Michael J Palladino, Ryan W Logan, Jill R Glausier, Kenneth N Fish, David A Lewis, J Timothy Greenamyre, Brian D McCabe, Claire E J Cheetham, Thomas S Hnasko, Zachary Freyberg 

Proc Natl Acad Sci U S A. 2021 Apr 27;
Temporally and spatially partitioned neuropeptide release from individual clock neurons
Markus K Klose, Marcel P Bruchez, David L Deitcher, Edwin S Levitan 

J Neurosci. 2021 Apr 23
VGLUT2 is a determinant of dopamine neuron resilience in a rotenone model of dopamine neurodegeneration
Silas A Buck, Briana R De Miranda, Ryan W Logan, Kenneth N Fish, J Timothy Greenamyre, Zachary Freyberg 

Cereb Cortex. 2021 Apr 19
Decoding of Attentional State Using High-Frequency Local Field Potential Is As Accurate As Using Spikes
Surya S Prakash, Aritra Das, Sidrat Tasawoor Kanth, J Patrick Mayo, Supratim Ray 

J Nucl Med. 2021 Apr 16
Direct comparison of the tau PET tracers [ 18 F]flortaucipir and [ 18 F]MK-6240 in human subjects
Alexandra Gogola, Davneet Singh Minhas, Victor L Villemagne, Ann D Cohen, James M Mountz, Tharick Ali Pascoal, Charles M Laymon, N Scott Mason, Milos D Ikonomovic, Chester A Mathis, Beth E Snitz, Oscar L Lopez, William E Klunk, Brian J Lopresti 

Annu Rev Neurosci. 2021 Apr 16.
The Cortical Motor Areas and the Emergence of Motor Skills: A Neuroanatomical Perspective
Peter L Strick, Richard P Dum, Jean-Alban Rathelot 

Neurotherapeutics. 2021 Apr 15
Ethical Considerations in Communicating Alzheimer's Disease Neuroimaging Biomarker Test Results to Symptomatic Individuals
Daniel A Wilkenfeld, Staci L Orbell, Jennifer H Lingler 

Cereb Cortex. 2021 Apr 12
The Brain Circuits and Dynamics of Curiosity-Driven Behavior in Naturally Curious Marmosets
Xiaoguang Tian, Afonso C Silva, Cirong Liu

Mol Psychiatry. 2021 Apr 9.
Astrocytes in cocaine addiction and beyond
Junshi Wang, Leanne M Holt, Hugh H Huang, Susan R Sesack, Eric J Nestler, Yan Dong 

Elife. 2021 Apr 6
Excitation of medium spiny neurons by 'inhibitory' ultrapotent chemogenetics via shifts in chloride reversal potential
Stephanie C Gantz, Maria M Ortiz, Andrew J Belilos, Khaled Moussawi 

Mov Disord. 2021 Apr 5
Lateralized Effect of Thalamic Deep Brain Stimulation Location on Verbal Abstraction
Dengyu Wang, Ahmed Jorge, Witold J Lipski, Ian H Kratter, Luke C Henry, R Mark Richardson 

J Cereb Blood Flow Metab. 2021 Apr 4
Three-dimensional remodeling of functional cerebrovascular architecture and gliovascular unit in leptin receptor-deficient mice
Yaan Liu, Di Chen, Amanda Smith, Qing Ye, Yanqin Gao, Wenting Zhang 

Nat Neurosci. 2021 Mar 29.
Learning is shaped by abrupt changes in neural engagement
Jay A Hennig, Emily R Oby, Matthew D Golub, Lindsay A Bahureksa, Patrick T Sadtler, Kristin M Quick, Stephen I Ryu, Elizabeth C Tyler-Kabara, Aaron P Batista #, Steven M Chase #, Byron M Yu #

Neuropsychopharmacology. 2021 Mar 29.
Neural function during emotion regulation and future depressive symptoms in youth at risk for affective disorders
Jay C Fournier #, Michele Bertocci # ,Cecile D Ladouceur, Lisa Bonar, Kelly Monk, Halimah Abdul-Waalee, Amelia Versace, João Paulo Lima Santos, Satish Iyengar, Boris Birmaher, Mary L Phillips

J Neurosci. 2021 Mar 24
Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus
Shawn F Sorrells, Mercedes F Paredes, Zhuangzhi Zhang, Gugene Kang, Oier Pastor-Alonso, Sean Biagiotti, Chloe E Page, Kadellyn Sandoval, Anthony Knox, Andrew Connolly, Eric J Huang, Jose Manuel Garcia-Verdugo, Michael C Oldham, Zhengang Yang, Arturo Alvarez-Buylla 

Psychol Med. 2021 March
Experimentally imposed circadian misalignment alters the neural response to monetary rewards and response inhibition in healthy adolescents
Brant P Hasler, Adriane M Soehner, Meredith L Wallace, Ryan W Logan, Wambui Ngari, Erika E Forbes, Daniel J Buysse, Duncan B Clark 

Cell. 2021 Mar 18
Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis
Shiqun Zhang, Tara N Edwards, Virendra K Chaudhri, Jianing Wu, Jonathan A Cohen, Toshiro Hirai, Natalie Rittenhouse, Elizabeth G Schmitz, Paul Yifan Zhou, Benjamin D McNeil, Yi Yang, Richard Koerber, Tina L Sumpter, Amanda C Poholek, Brian M Davis, Kathryn M Albers, Harinder Singh, Daniel H Kaplan 

Am J Psychiatry. 2021 Mar 17
Effect of Experimental Manipulation of the Orbitofrontal Cortex on Short-Term Markers of Compulsive Behavior: A Theta Burst Stimulation Study
Rebecca B Price, Claire M Gillan. Colleen Hanlon, Fabio Ferrarelli, Tae Kim, Helmet T Karim, Marlee Renard, Rachel Kaskie, Michelle Degutis, Anna Wears, Emelina P Vienneau, Angel V Peterchev,, Vanessa Brown, Greg J Siegle, Meredith L Wallace, Susanne E Ahmari 

Am J Psychiatry. 2021 Mar 17
Sleep Abnormalities in Schizophrenia: State of the Art and Next Steps
Fabio Ferrarelli

J Neurosci. 2021 Mar 16
Mechanism of pacemaker activity in zebrafish DC2/4 dopaminergic neurons
Vladimir A Ilin, Qing Bai, Alan M Watson, Maxim Volgushev, Edward A Burton 

Transl Psychiatry. 2021 Mar 15
Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder
Sean C Piantadosi, Lora L McClain, Lambertus Klei, Jiebiao Wang, Brittany L Chamberlain, Sara A Springer, David A Lewis, Bernie Devlin, Susanne E Ahmari 

Br J Anaesth. 2021 Mar 10
Mechanistic insights into spinal neurones involved in neuraxial opioid-induced pruritus
Eileen Nguyen, Grace Lim, Sarah E Ross

Biol Psychiatry. 2021 Mar 8
Sex Differences in Molecular Rhythms in the Human Cortex
Ryan W Logan, Xiangning Xue, Kyle D Ketchesin Gabriel Hoffman, Panos Roussos, George Tseng, Colleen A McClung, Marianne L Seney 

Nat Neurosci. 2021 Mar 8
Rare rewards amplify dopamine responses
Kathryn M Rothenhoefer, Tao Hong, Aydin Alikaya, William R Stauffer

Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Mar 5
μ-Opioid antagonist naltrexone partially abolishes the antidepressant placebo effect and reduces OFC encoding of reinforcement
Marta Peciña, Jiazhou Chen, Thandi Lyew, Jordan F Karp, Alexandre Y Dombrovski

Am J Psychiatry. 2021 Mar 3
Examining and Modulating Neural Circuits in Psychiatric Disorders With Transcranial Magnetic Stimulation and Electroencephalography: Present Practices and Future Developments
Fabio Ferrarelli, Mary L Phillips 

Prog Neurobiol. 2021 Mar 2
Dopamine-related striatal neurophysiology is associated with specialization of frontostriatal reward circuitry through adolescence
Ashley C Parr, Finnegan Calabro, Bart Larsen, Brenden Tervo-Clemmens, Samuel Elliot, Will Foran, Valur Olafsson, Beatriz Luna 

Biol Psychiatry. 2021 Feb 19
Altered Parvalbumin Basket Cell Terminals in the Cortical Visuospatial Working Memory Network in Schizophrenia
Kenneth N Fish, Brad R Rocco, Adam M DeDionisio, Samuel J Dienel, Robert A Sweet, David A Lewis 

Neuroimage. 2021 Feb 17
The longitudinal stability of fMRI activation during reward processing in adolescents and young adults
David A A Baranger, Morgan Lindenmuth, Melissa Nance, Amanda E Guyer, Kate Keenan, Alison E Hipwell, Daniel S Shaw, Erika E Forbes 

Transl Psychiatry. 2021 Feb 16
Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors
Despoina Aslanoglou, Suzanne Bertera, Marta Sánchez-Soto, R Benjamin Free, Jeongkyung Lee, Wei Zong, Xiangning Xue, Shristi Shrestha, Marcela Brissova, Ryan W Logan, Claes B Wollheim, Massimo Trucco, Vijay K Yechoor,  David R Sibley, Rita Bottino, Zachary Freyberg 

Acta Neuropathol. 2021 Feb 14.
Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology
Nicholas J Ashton, Tharick A Pascoal, Thomas K Karikari, Andréa L Benedet, Juan Lantero-Rodriguez, Gunnar Brinkmalm, Anniina Snellman, Michael Schöll, Claire Troakes, Abdul Hye, Serge Gauthier, Eugeen Vanmechelen, Henrik Zetterberg, Pedro Rosa-Neto, Kaj Blennow

J Neurosci. 2021 Feb 10;
Outer hair cell glutamate signaling through type II spiral ganglion afferents activates neurons in the cochlear nucleus in response to non-damaging sounds
Catherine J C Weisz, Sean-Paul G Williams, Chad S Eckard, Christopher B Divito, David W Ferreira, Kristen N Fantetti, Shenin A Dettwyler, Hou-Ming Cai, Maria E Rubio, Karl Kandler, Rebecca P Seal 

Sci Transl Med. 2021 Feb 3
Morphine acts on spinal dynorphin neurons to cause itch through disinhibition
Eileen Nguyen, Grace Lim, Huiping Ding, Junichi Hachisuka, Mei-Chuan Ko, Sarah E Ross 

PLoS Pathog. 2021 Feb 3;
Physiological and immunological changes in the brain associated with lethal eastern equine encephalitis virus in macaques
Joseph R Albe, Henry Ma, Theron H Gilliland, Cynthia M McMillen, Christina L Gardner, Devin A Boyles, Emily L Cottle, Matthew D Dunn, Jeneveve D Lundy, Katherine J O'Malley, Noah Salama, Aaron W Walters, Ivona Pandrea, Tobias Teichert, William B Klimstra, Douglas S Reed, Amy L Hartman 

Mol Psychiatry. 2021 Feb 1
MAP2 is differentially phosphorylated in schizophrenia, altering its function
M J Grubisha, X Sun, M L MacDonald, M Garver, Z Sun, K A Paris, D S Patel, R A DeGiosio, D A Lewis, N A Yates, C Camacho, G E Homanics, Y Ding, R A Sweet

Biol Psychiatry. 2021 Feb 1
Prepubertal Environmental Enrichment Prevents Dopamine Dysregulation and Hippocampal Hyperactivity in MAM Schizophrenia Model Rats
Xiyu Zhu, Anthony A Grace

Mol Psychiatry. 2021 Jan 25
A specific neural substrate predicting current and future impulsivity in young adults
J Scott Steele, Michele Bertocci, Kristen Eckstrand, Henry W Chase, Richelle Stiffler, Haris Aslam, Jeanette Lockovich, Genna Bebko, Mary L Phillips

Am J Psychiatry. 2021 Jan 21;
Association of Neural Reward Circuitry Function With Response to Psychotherapy in Youths With Anxiety Disorders
Stefanie L Sequeira, Jennifer S Silk, Cecile D Ladouceur, Jamie L Hanson, Neal D Ryan, Judith K Morgan, Dana L McMakin, Philip C Kendall, Ronald E Dahl, Erika E Forbes

Dev Cogn Neurosci. 2021 Jan 20;
Lower neural value signaling in the prefrontal cortex is related to childhood family income and depressive symptomatology during adolescence
Esther E Palacios-Barrios, Jamie L Hanson, Kelly R Barr, W Dustin Albert, Stuart F White, Ann T Skinner, Kenneth A Dodge, Jennifer E Lansford 

Nat Commun. 2021 Jan 19
Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cordNathan Greiner, Beatrice Barra, Giuseppe Schiavone, Henri Lorach, Nicholas James, Sara Conti, Melanie Kaeser, Florian Fallegger, Simon Borgognon, Stéphanie Lacour, Jocelyne Bloch, Grégoire Courtine, Marco Capogrosso

Radiology. 2021 Jan 19
Molecular Imaging Approaches in Dementia
Victor L Villemagne, Frederik Barkhof, Valentina Garibotto, Susan M Landau, Agneta Nordberg, Bart N M van Berckel

Neuropsychopharmacology. 2021 Jan 15.
Beta-adrenergic blockade blunts inflammatory and antiviral/antibody gene expression responses to acute psychosocial stress
Jennifer K MacCormack, Monica M Gaudier-Diaz, Emma L Armstrong-Carter, Jesusa M G Arevalo, Samantha Meltzer-Brody, Erica K Sloan, Steven W Cole, Keely A Muscatell 

Biol Psychiatry. 2021 Jan 15
Considerations When Characterizing Adolescent Neurocognitive Development
Beatriz Luna, Brenden Tervo-Clemmens, Finnegan J Calabro 

Schizophr Bull. 2021 Jan 14
Similarities in Cortical Transcriptome Alterations Between Schizophrenia and Bipolar Disorder Are Related to the Presence of Psychosis
John F Enwright, David A Lewis 

Transl Psychiatry. 2021 Jan 12;
Involvement of the nuclear factor-κB transcriptional complex in prefrontal cortex immune activation in bipolar disorder
Kaitlyn M Roman, Aaron K Jenkins, David A Lewis, David W Volk 

J Neurosci. 2021 Jan 12
AMPA and NMDA Receptor Trafficking at Cocaine-Generated Synapses
Yao Q Wang, Yanhua H Huang, Saju Balakrishnan, Li-Dong Liu, Yu Tian Wang, Eric J Nestle,, Oliver M Schlüter, Yan Dong 

Proc Natl Acad Sci U S A. 2021 Jan 12
Diurnal rhythms across the human dorsal and ventral striatum
Kyle D Ketchesin, Wei Zong, Mariah A Hildebrand, Marianne L Seney, Kelly M Cahill, Madeline R Scott, Vaishnavi G Shankar, Jill R Glausier, David A Lewis, George C Tseng, Colleen A McClung

Neurobiol Dis. 2021 Jan 9
nhibition of TGFβ-activated kinase 1 promotes inflammation-resolving microglial/macrophage responses and recovery after stroke in ovariectomized female mice
Yaan Liu, Sicheng Li, Rongrong Wang, Hongjian Pu, Yongfang Zhao, Qing Ye, Yejie Shi 

Autophagy. 2021 Jan 6.
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes
Meysam Yazdankhah, Sayan Ghosh, Peng Shang, Nadezda Stepicheva, Stacey Hose, Haitao Liu, Xitiz Chamling, Shenghe Tian, Mara L G Sullivan, Michael Joseph Calderon, Christopher S Fitting, Joseph Weiss, Ashwath Jayagopal, James T Handa, José-Alain Sahel, J Samuel Zigler Jr Paul R Kinchington, Donald J Zack, Debasish Sinha 

 

Neurology. 2021 Jan 4
Cell Therapy for Chronic TBI: Interim Analysis of the Randomized Controlled STEMTRA Trial
Masahito Kawabori, Alan H Weintraub, Hideaki Imai, Laroslav Zinkevych, Peter McAllister, Gary K Steinberg, Benjamin M Frishberg, Takao Yasuhara, Jefferson W Chen, Steven C Cramer, Achal S Achrol, Neil E Schwartz, Jun Suenaga, Daniel C Lu, Ihor Semeniv, Hajime Nakamura, Douglas Kondziolka, Dai Chida, Takehiko Kaneko, Yasuaki Karasawa, Susan Paadre, Bijan Nejadnik, Damien Bates, Anthony H Stonehouse, R Mark Richardson, David O Okonkwo

Philos Trans R Soc Lond B Biol Sc. 2021 Jan 4
Time-dependent spatial specificity of high-resolution fMRI: insights into mesoscopic neurovascular coupling
Mitsuhiro Fukuda, Alexander J Poplawsky, Seong-Gi Kim

Neuropsychopharmacology. 2021 January
Critical roles for developmental hormones and genetic sex in stress-induced transcriptional changes associated with depression
Marianne L Seney, Ryan W Logan

Methods Mol Biol. 2021
Measuring the Effects of Circadian Rhythm-Related Manipulations on Depression-Like Behavior in Rodents: Forced Swim and Tail Suspension Tests
Chelsea A Vadnie, Lauren M DePoy, Colleen A McClung