2019 Research

Here is a sample of Pitt research published in 2019 in journals with impact factors of 5 or higher. Click on the journal title to read a specific PubMed citation.


Biol Psychiatry. 2019 Dec 1
A Model of Restraint: Nucleus Accumbens Fast-Spiking Interneurons Inhibit Unwanted Actions.
Corbit VL, Gittis AH, Ahmari SE

Cell Rep. 2019 Nov 12
Abnormal Striatal Development Underlies the Early Onset of Behavioral Deficits in Shank3B-/- Mice.
Peixoto RT, Chantranupong L, Hakim R, Levasseur J, Wang W, Merchant T, Gorman K, Budnik B, Sabatini BL

Biol Psychiatry. 2019 Nov 1
Adapting Social Defeat Stress for Female Mice Using Species-Typical Interfemale Aggression.
Logan RW

Cereb Cortex. 2019 Oct 31
Development of Hippocampal-Prefrontal Cortex Interactions through Adolescence.
Calabro FJ, Murty VP, Jalbrzikowski M, Tervo-Clemmens B, Luna B

Mol Psychiatry. 2019 Oct 29
The impact of targeted cathodal transcranial direct current stimulation on reward circuitry and affect in Bipolar Disorder.
Bertocci MA, Chase HW, Graur S, Stiffler R, Edmiston EK, Coffman BA, Greenberg BD, Phillips ML

JAMA Psychiatry. 2019 Oct 23
Synaptic Proteome Alterations in the Primary Auditory Cortex of Individuals With Schizophrenia.
MacDonald ML, Garver M, Newman J, Sun Z, Kannarkat J, Salisbury R, Glausier J, Ding Y, Lewis DA, Yates N, Sweet RA

Nat Neurosci. 2019 Oct 21
Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence.
Chow HM, Shi M, Cheng A, Gao Y, Chen G, Song X, So RWL, Zhang J, Herrup K

Curr Opin Neurobiol. 2019 Oct 18
Editorial overview: Computational neuroscience.
Doiron B, Lengyel M

JCI Insight. 2019 Oct 17
STAT6/Arg1 promotes microglia/macrophage efferocytosis and inflammation resolution in stroke mice.
Cai W, Dai X, Chen J, Zhao J, Xu M, Zhang L, Yang B, Zhang W, Rocha M, Nakao T, Kofler J, Shi Y, Stetler RA1, Hu X, Chen J

J Neurosci. 2019 Oct 16
Parabrachial Complex: A Hub for Pain and Aversion.
Chiang MC, Bowen A, Schier LA, Tupone D, Uddin O, Heinricher MM

Neurobiol Dis. 2019 Oct 13
LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease.
Rocha EM, De Miranda BR, Castro S, Drolet R, Hatcher NG, Yao L, Smith SM, Keeney MT, Di Maio R, Kofler J, Hastings TG, Greenamyre JT

Pain. 2019 Oct 1
Selective-cold output via a distinct subset of lamina I spinoparabrachial neurons.
Hachisuka J, Koerber HR, Ross SE

Lancet Neurol. 2019 October
International traumatic brain injury research: an annus mirabilis?
Bell MJ, Kochanek PM

World Psychiatry. 2019 October
The network approach to psychopathology: promise versus reality.
Forbes MK, Wright AGC, Markon KE, Krueger RF

Biomaterials. 2019 Sep 30
Zwitterionic polymer/polydopamine coating reduce acute inflammatory tissue responses to neural implants.
Golabchi A, Wu B, Cao B, Bettinger CJ, Cui XT

J Cereb Blood Flow Metab. 2019 Sep 29
Robust RBM3 and β-klotho expression in developing neurons in the human brain.
Jackson TC, Janesko-Feldman K, Carlson SW, Kotermanski SE, Kochanek PM

Anal Chem. 2019 Sep 26
Direct in Vivo Electrochemical Detection of Resting Dopamine Using Poly(3,4-ethylenedioxythiophene)/Carbon Nanotube Functionalized Microelectrodes.
Taylor IM, Patel NA, Freedman NC, Castagnola E, Cui XT

Mol Psychiatry. 2019 Sep 5
The pathophysiological impact of stress on the dopamine system is dependent on the state of the critical period of vulnerability.
Gomes FV, Zhu X, Grace AA

Trends Neurosci. 2019 September
Neural Substrates of Inhibitory Control Maturation in Adolescence.
Constantinidis C, Luna B

Nat Biomed Eng. 2019 September
Pipette-integrated microelectrodes.
Kozai TDY, Purcell EK

Neuropsychopharmacology. 2019 Aug 28
Orbitofrontal cortex is selectively activated in a primate model of attentional bias to cocaine cues.
Baeg E, Jedema HP, Bradberry CW

Neuroimage. 2019 Aug 28
Differential tractography as a track-based biomarker for neuronal injury.
Yeh FC, Zaydan IM, Suski VR, Lacomis D, Richardson RM, Maroon JC, Barrios-Martinez J

Mol Psychiatry. 2019 Aug 27
Transcranial direct current stimulation: a roadmap for research, from mechanism of action to clinical implementation.
Chase HW, Boudewyn MA, Carter CS, Phillips ML

Brain Behav Immun. 2019 Aug 22
Retrospectively reported childhood physical abuse, systemic inflammation, and resting corticolimbic connectivity in midlife adults.
Kraynak TE, Marsland AL, Hanson JL, Gianaros PJ

Pain. 2019 August
An NPY Y1 receptor antagonist unmasks latent sensitization and reveals the contribution of protein kinase A and Epac to chronic inflammatory pain.
Fu W, Nelson TS, Santos DF, Doolen S, Gutierrez JJP, Ye N, Zhou J, K Taylor B

Schizophr Bull. 2019 Jul 29
Vesicular Antipsychotic Drug Release Evokes an Extra Phase of Dopamine Transmission.
Walters SH, Levitan ES

Proc Natl Acad Sci U S A. 2019 Jul 25
Mutant huntingtin disrupts mitochondrial proteostasis by interacting with TIM23.
Yablonska S, Ganesan V, Ferrando LM, Kim J, Pyzel A, Baranova OV, Khattar NK, Larkin TM, Baranov SV, Chen N, Strohlein CE, Stevens DA1, Wang X, Chang YF, Schurdak ME, Carlisle DL, Minden JS, Friedlander RM

Am J Obstet Gynecol. 2019 Jul 16
Opioids Affect the Fetal Brain: Reframing the Detoxification Debate.
Caritis SN, Panigrahy A

J Clin Invest. 2019 Jul 15
Persistent HIV-infected cells in cerebrospinal fluid are associated with poorer neurocognitive performance.
Spudich S, Robertson KR, Bosch RJ, Gandhi RT, Cyktor JC, Mar H, Macatangay BJ, Lalama CM, Rinaldo C, Collier AC, Godfrey C, Eron JJ, McMahon D, Jacobs JL, Koontz D, Hogg E, Vecchio A, Mellors JW

J Neurosci. 2019 Jul 11
Binding during sequence learning does not alter cortical representations of individual actions.
Beukema P, Diedrichsen J, Verstynen T

Neuropsychopharmacology. 2019 Jul 1
The medial septum enhances reversal learning via opposing actions on ventral tegmental area and substantia nigra dopamine neurons.
Bortz DM, Gazo KL, Grace AA

Alzheimers Dement. 2019 Jun 26
Blood amyloid levels and risk of dementia in the Ginkgo Evaluation of Memory Study (GEMS): A longitudinal analysis.
Lopez OL, Chang Y, Ives DG, Snitz BE, Fitzpatrick AL, Carlson MC, Rapp SR, Williamson JD, Tracy RP, DeKosky ST, Kuller LH

PLoS Biol. 2019 Jun 21
The interleukin-4/PPARγ signaling axis promotes oligodendrocyte differentiation and remyelination after brain injury.
Zhang Q, Zhu W, Xu F, Dai X, Shi L, Cai W, Mu H, Hitchens TK, Foley LM, Liu X, Yu F, Chen J, Shi Y, Leak RK, Gao Y, Chen J, Hu X

PLoS Pathog. 2019 Jun 20
Neutrophil and macrophage influx into the central nervous system are inflammatory components of lethal Rift Valley fever encephalitis in rats.
Albe JR, Boyles DA, Walters AW, Kujawa MR, McMillen CM, Reed DS, Hartman AL

JAMA Psychiatry. 2019 Jun 5
Insights Into the Pathophysiology of Endocannabinoid Signaling in Schizophrenia.
Volk DW, Lewis DA

Schizophr Bull. 2019 May 31
Intrinsic Connectivity of the Globus Pallidus: An Uncharted Marker of Functional Prognosis in People With First-Episode Schizophrenia.
Tarcijonas G, Foran W, Haas GL1, Luna B, Sarpal DK

Neuroimage. 2019 May 30
Quantitatively validating the efficacy of artifact suppression techniques to study the cortical consequences of deep brain stimulation with magnetoencephalography.
Boring MJ, Jessen ZF, Wozny TA, Ward MJ, Whiteman AC, Richardson RM, Ghuman AS

Sci Transl Med. 2019 May 29
Depicting brighter possibilities for treating blindness.
Sahel JA, Bennett J, Roska B

J Am Acad Child Adolesc Psychiatry. 2019 May 28
Editorial: What Do Cannabis-Related Differences in Corticostriatal Circuitry Subserving Cognitive Control Mean?
Baranger DAA, Bogdan R

J Neurosci. 2019 May 28
Growth factor signaling regulates mechanical nociception in flies and vertebrates.
Lopez-Bellido R, Puig S, Huang PJ, Tsai CR, Turner HN, Galko MJ, Gutstein HB

Trends Cogn Sci. 2019 May 15
Dynamic Neural Representations: An Inferential Challenge for fMRI.
Ghuman AS, Martin A

JAMA Psychiatry. 2019 May 8
Anhedonia Reduction and the Association Between Left Ventral Striatal Reward Response and 6-Month Improvement in Life Satisfaction Among Young Adults.
Eckstrand KL, Forbes EE, Bertocci MA, Chase HW, Greenberg T, Lockovich J, Stiffler R, Aslam HA, Graur S, Bebko G, Phillips ML

J Neurosci. 2019 May 8
Neuronal effects of spatial and feature attention differ due to normalization.
Ni AM, Maunsell JHR

Biochim Biophys Acta Mol Basis Dis. 2019 May 7
Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Roland BP, Richards KR, Hrizo SL, Eicher S, Barile ZJ, Chang TC, Savon G, Bianchi P, Fermo E, Ricerca BM, Tortorolo L, Vockley J, VanDemark AP, Palladino MJ

Am J Psychiatry. 2019 May 6
Nociceptin Receptors Upregulated in Cocaine Use Disorder: A Positron Emission Tomography Imaging Study Using [11C]NOP-1A.
Narendran R, Tollefson S, Himes ML, Paris J, Lopresti B, Ciccocioppo R, Mason NS

Gastroenterology. 2019 Apr 28
Extrinsic Primary Afferent Neurons Link Visceral Pain to Colon Motility Through a Spinal Reflex in Mice.
Smith-Edwards KM, Najjar SA, Edwards BS, Howard MJ, Albers KM, Davis BM

Proc Natl Acad Sci U S A. 2019 Apr 17
Protease-independent action of tissue plasminogen activator in brain plasticity and neurological recovery after ischemic stroke.
Pu H, Shi Y, Zhang L, Lu Z, Ye Q, Leak RK, Xu F, Ma S, Mu H, Wei Z, Xu N, Xia Y, Hu X, Hitchens TK, Bennett MVL, Chen J

JAMA Psychiatry. 2019 Apr 17
Can Network Meta-analysis Substitute for Direct Comparisons in Psychotherapy Trials?
Swartz HA, Fournier J

JAMA Neurol. 2019 Apr 15
Association of Closed-Loop Brain Stimulation Neurophysiological Features With Seizure Control Among Patients With Focal Epilepsy.
Kokkinos V, Sisterson ND, Wozny TA, Richardson RM

Mol Psychiatry. 2019 Apr 12
Chronic sleep fragmentation enhances habenula cholinergic neural activity.
Ge F, Mu P, Guo R, Cai L, Liu Z, Dong Y, Huang YH

J Neurosci. 2019 Apr 3
Subthalamic Nucleus and Sensorimotor Cortex Activity During Speech Production.
Chrabaszcz A, Neumann WJ, Stretcu O, Lipski WJ, Bush A, Dastolfo-Hromack CA, Wang D, Crammond DJ, Shaiman S, Dickey MW, Holt LL, Turner RS, Fiez JA, Richardson RM

Cell Rep. 2019 Apr 2
Dopamine Modulation of Prefrontal Cortex Activity Is Manifold and Operates at Multiple Temporal and Spatial Scales.
Lohani S, Martig AK, Deisseroth K, Witten IB, Moghaddam B

Br J Pharmacol. 2019 Mar 29
Therapeutic Targeting of Nuclear Receptors, LXR and RXR, for Alzheimer's Disease.
Fitz NF, Nam KN, Koldamova R, Lefterov I

Nat Commun. 2019 Mar 21
Optimal features for auditory categorization.
Liu ST, Montes-Lourido P, Wang X, Sadagopan S

Psychol Med. 2019 Mar 14
Proxy measures of premortem cognitive aptitude in postmortem subjects with schizophrenia.
Glausier JR, Kelly MA, Salem S, Chen K, Lewis DA

Stroke. 2019 Mar 13
A Novel Na+-K+-Cl- Cotransporter 1 Inhibitor STS66 Reduces Brain Damage in Mice After Ischemic Stroke.
Huang H, Bhuiyan MIH, Jiang T, Song S, Shankar S, Taheri T, Li E, Schreppel P, Hintersteininger M, Yang SS, Lin SH, Molyneaux BJ, Zhang Z, Erker T, Sun D

Adv Healthc Mater. 2019 Mar 6
Soft Conducting Elastomer for Peripheral Nerve Interface.
Zheng X, Woeppel KM, Griffith AY, Chang E, Looker MJ, Fisher LE, Clapsaddle BJ, Cui XT

J Cereb Blood Flow Metab. 2019 Mar 5
TGFα preserves oligodendrocyte lineage cells and improves white matter integrity after cerebral ischemia.
Dai X, Chen J, Xu F, Zhao J, Cai W, Sun Z, Hitchens TK, Foley LM, Leak RK, Chen J, Hu X

Biomaterials. 2019 March
Meningeal inflammatory response and fibrous tissue remodeling around intracortical implants: An in vivo two-photon imaging study.
Eles JR, Vazquez AL, Kozai TDY, Cui XT

Transl Stroke Res. 2019 Feb 28
Intracerebroventricular Delivery of Recombinant NAMPT Deters Inflammation and Protects Against Cerebral Ischemia.
Chen F, Weng Z, Xia Q, Cao C, Leak RK, Han L, Xiao J, Graham SH, Cao G

Neuropsychopharmacology. 2019 Feb 25
Reduced focal fiber collinearity in the cingulum bundle in adults with obsessive-compulsive disorder.Versace A, Graur S, Greenberg T, Lima Santos JP, Chase HW, Bonar L, Stiffler RS, Hudak R, Kim T, Yendiki A, Greenberg B, Rasmussen S, Liu H, Haber S, Phillips ML

Neuroimage. 2019 Feb 23
Word inversion sensitivity as a marker of visual word form area lateralization: An application of a novel multivariate measure of laterality.
Carlos BJ, Hirshorn EA, Durisko C, Fiez JA, Coutanche MN

Neuropsychopharmacology. 2019 Feb 22
Density of small dendritic spines and microtubule-associated-protein-2 immunoreactivity in the primary auditory cortex of subjects with schizophrenia.
McKinney BC, MacDonald ML, Newman JT, Shelton MA, DeGiosio RA, Kelly RM, Fish KN, Sampson AR, Lewis DA, Sweet RA

Biomaterials. 2019 Feb 19
Conduits harnessing spatially controlled cell-secreted neurotrophic factors improve peripheral nerve regeneration.
Sun AX, Prest TA, Fowler JR, Brick RM, Gloss KM, Li X, DeHart M, Shen H, Yang G, Brown BN, Alexander PG, Tuan RS

Free Radic Biol Med. 2019 Feb 18
An augmentation in histone dimethylation at lysine nine residues elicits vision impairment following traumatic brain injury.
Gupta R, Saha P, Sen T, Sen N

Proc Natl Acad Sci U S A. 2019 Feb 13
Role of UCHL1 in axonal injury and functional recovery after cerebral ischemia.
Liu H, Povysheva N, Rose ME, Mi Z, Banton JS, Li W, Chen F, Reay DP, Barrionuevo G, Zhang F, Graham SH

Neuropsychopharmacology. 2019 Feb 13
Baseline and follow-up activity and functional connectivity in reward neural circuitries in offspring at risk for bipolar disorder.
Acuff HE, Versace A, Bertocci MA, Ladouceur CD, Hanford LC, Manelis A, Monk K, Bonar L, McCaffrey A, Goldstein BI, Goldstein TR, Sakolsky D, Axelson D, Birmaher B, Phillips ML

Neuroimage. 2019 Feb 9
An increase in sleep slow waves predicts better working memory performance in healthy individuals.
Ferrarelli F, Kaskie R, Laxminarayan S, Ramakrishnan S, Reifman J, Germain A

J Neurosci. 2019 Feb 8
Strengthened inputs from secondary motor cortex to striatum in a mouse model of compulsive behavior.
Corbit VL, Manning EE, Gittis AH, Ahmari SE

J Am Acad Child Adolesc Psychiatry. 2019 February
Amygdala Functional Connectivity During Self-Face Processing in Depressed Adolescents With Recent Suicide Attempt.
Alarcón G, Sauder M, Teoh JY, Forbes EE, Quevedo K

JACC Heart Fail. 2019 February
Amyloidosis of the Brain and Heart: Two Sides of the Same Coin?
Schaich CL, Maurer MS, Nadkarni NK

J Neurosci. 2019 Jan 30
Subthalamic nucleus and sensorimotor cortex activity during speech production.
Chrabaszcz A, Neumann WJ, Stretcu O, Lipski WJ, Bush A, Dastolfo-Hromack C, Wang D4, Crammond DJ, Shaiman S, Dickey MW, Holt LL, Turner RS, Fiez JARichardson RM

PLoS Genet. 2019 Jan 29
Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation.
Hanovice NJ, Leach LL, Slater K, Gabriel AE, Romanovicz D, Shao E, Collery R, Burton EA, Lathrop KL, Link BA, Gross JM

Am J Psychiatry. 2019 Jan 18
Age-Associated Deviations of Amygdala Functional Connectivity in Youths With Psychosis Spectrum Disorders: Relevance to Psychotic Symptoms.
Jalbrzikowski M, Murty VP, Tervo-Clemmens B, Foran W, Luna B

J Am Acad Child Adolesc Psychiatry. 2019 Jan 17
Structural Brain Alterations in Youth With Psychosis and Bipolar Spectrum Symptoms.
Jalbrzikowski M, Freedman D, Hegarty CE, Mennigen E, Karlsgodt KH, Olde Loohuis LM, Ophoff RA, Gur RE, Bearden CE

Neurobiol Dis. 2019 Jan 15
Long-term RNAi knockdown of α-synuclein in the adult rat substantia nigra without neurodegeneration.
Zharikov A, Bai Q, De Miranda BR, Van Laar A, Timothy Greenamyre J, Burton EA

Neurotherapeutics. 2019 Jan 3
Toward Electrophysiology-Based Intelligent Adaptive Deep Brain Stimulation for Movement Disorders.
Neumann WJ, Turner RS, Blankertz B, Mitchell T, Kühn AA, Mark Richardson R

Neuroimage. 2019 Jan 1
Irritability uniquely predicts prefrontal cortex activation during preschool inhibitory control among all temperament domains: A LASSO approach.
Fishburn FA, Hlutkowsky CO, Bemis LM, Huppert TJ, Wakschlag LS, Perlman SB

Neurobiol Dis. 2019 January
What is the functional relevance of reorganization in primary motor cortex after spinal cord injury?
Urbin MA, Royston DA, Weber DJ, Boninger ML, Collinger JL

Stroke. 2019 January
High Variability in Neuronal Loss.
Desai SM, Rocha M, Jovin TG, Jadhav AP

Neurobiol Aging. 2019 January
Comparison of longitudinal Aβ in nondemented elderly and Down syndrome.
Tudorascu DL, Anderson SJ, Minhas DS, Yu Z, Comer D, Lao P, Hartley S, Laymon CM, Snitz BE, Lopresti BJ, Johnson S, Price JC, Mathis CA, Aizenstein HJ, Klunk WE, Handen BL, Christian BT, Cohen AD